From Taxus to paclitaxel: Opportunities and challenges for urban agriculture to promote human health

Urban Farm DB summary

This review examines sustainable production of paclitaxel, an anti-cancer compound derived from Taxus (yew) trees, in the context of urban agriculture. It notes that traditional extraction methods from Taxus are inefficient and destructive, risking extinction of the genus, and surveys research on biotechnological approaches to efficient, cost-effective paclitaxel biosynthesis. The review discusses strategies for industrial-scale production based on Taxus cell culture methods.